Role of MicroRNAs in Insect Host–Microorganism Interactions
نویسنده
چکیده
MicroRNAs (miRNAs) have appeared as important regulators of various biological processes including development, cancer, immunity, and host-microorganism interactions. Accumulating evidence demonstrates the differential expression of host miRNAs upon infection by various microorganisms and the involvement of microorganism-encoded miRNAs in host manipulation. Some of these alterations could be part of a host response to an infection to limit replication and dissemination of the microorganism or, conversely, due to manipulation of the host miRNA pathway by the microorganism to facilitate its replication. Insights into the role of miRNAs in host defense responses and host manipulation by microorganisms will enable a better understanding of host-microorganism interactions.
منابع مشابه
Regulatory role of cellular and viral microRNAs in insect–virus interactions
98 99 100 101 The discovery of microRNAs (miRNAs) and their functions has led to a paradigm shift in our understanding of the regulation of gene expression, adding an extra layer of complexity for the mechanisms of gene expression. Both cellular and virus encoded miRNAs play important roles in virus–host interactions that may affect virus replication and the outcome of infection. Recent develop...
متن کاملFunctional analysis of a cellular microRNA in insect host-ascovirus interaction.
MicroRNAs (miRNAs) have emerged as key regulators in many biological processes, from development to defense, at almost all organismal levels. Recently, their role has been highlighted in pathogen-host interactions. Emerging evidence from a variety of virus-host systems indicates that cellular as well as virally encoded miRNAs influence viral replication. Here, we report changes in expression le...
متن کاملNovel Insights into Insect-Microbe Interactions—Role of Epigenomics and Small RNAs
It has become increasingly clear that microbes form close associations with the vast majority of animal species, especially insects. In fact, an array of diverse microbes is known to form shared metabolic pathways with their insect hosts. A growing area of research in insect-microbe interactions, notably for hemipteran insects and their mutualistic symbionts, is to elucidate the regulation of t...
متن کاملThe role of microRNAs and phytohormones in plant immune system
The plant-pathogen interaction is a multifactor process that may lead to resistance or susceptible responses of plant to pathogens. During the arms race between plant and pathogens, various biochemical, molecular and physiological events are triggered in plant cells such as ROS signaling, hormone activation and gene expression reprogramming. In plants, microRNAs (miRNAs) are key post-transcript...
متن کاملDiscovering microRNAs from Bombyx mori nucleopolyhedrosis virus.
MicroRNAs (miRNAs) have emerged as key players in host-pathogen interaction. Recently, many virus-encoded miRNAs have been identified from different mammalian species. However, the large family of invertebrate viruses of Baculoviridae, which infects diverse species of beneficial insects and agriculture pests, has hardly been investigated for elucidating the role of miRNAs in host-pathogen inter...
متن کامل